Isn't it little early to talk about the ending...?
I'm sure Ed and Winry will survive, end up together, get married, have children etc etc.. *Boo-oo-oooring*
But well, I'd say Arakawa could kill Wrath. Maybe all other homunculi also.. No, we can't let cute little Pride or my lovely Greed-sama-Ling to die.. xC Eventually, Ling should get his body back completely..
And Riza, or Roy.. I just can't imagine they would both survive..